Prickly Pear Uses, Benefits & Dosage

Scientific Identify(s): Opuntia ficus-indica (L.) Mill., Opuntia fragilis (Nutt.) Haw., Opuntia streptacantha Lem., Opuntia tuna (L.) Mill.
Frequent Identify(s): Nopal, Prickly pear, Tuna

Medically reviewed by Medicine.com. Final up to date on Mar 16, 2020.

Scientific Overview

Use

Prickly pear is broadly cultivated and commercially utilized in juices, jellies, candies, teas, and alcoholic drinks. American Indians used prickly pear juice to deal with burns, and prickly pear has an extended historical past in conventional Mexican people medication for treating diabetes. Its use in treating diabetes, lipid issues, irritation, and ulcers, in addition to its different pharmacologic results, have been documented. Nevertheless, there may be restricted medical info to help these makes use of.

Dosing

Prickly pear is commercially obtainable in quite a few doseforms, together with capsules, tablets, powders, and juices, and as meals. Comply with producers’ recommended pointers if utilizing industrial merchandise. Typical dosage regimens are two 250 mg capsules by mouth Three instances a day or each Eight hours.

Contraindications

Hypersensitivity to any parts of prickly pear.

Being pregnant/Lactation

Keep away from use throughout being pregnant and lactation due to the dearth of medical research.

Interactions

None nicely documented.

Adversarial Reactions

Dermatitis is the most typical antagonistic response to prickly pear.

Toxicology

Little info is offered.

Scientific Household

Botany

Prickly pears are members of the Cactacceae or cactus household, which incorporates about 97 genera and 1,600 species. The species are present in Europe, Mediterranean nations, Africa, southwestern United States, and northern Mexico. Vegetation within the genus Opuntia choose a dry, scorching local weather and encompass perennial shrubs, bushes, and creeping crops. Prickly pear can develop 5 to eight m in peak; its roots are shallow, however the plant can unfold as much as 40 m in diameter over the bottom. The stems are branched, leaves are cylindrical in form, and the plant is roofed with barb-tipped bristles (generally known as glochids) which are distinctive to Opuntia. Its flowers, petals, and sepals are quite a few in amount and coloration. The oval, pear-shaped, purplish fruit is pulpy and candy however could also be lined with spines or bristles. The seeds throughout the pulp are disk-shaped and have quite a few colours.1, 2, 3, 5, 6, 7

As a result of info on this species as a complete is sparse, the next subspecies are additionally included in numerous points of the dialogue: Opuntia fulginosa, Opuntia megacantha, Opuntia dillenii, Opuntia microdasys, Opuntia bieglovii, Opuntia acanthocarpa.

Historical past

Prickly pear is broadly cultivated and utilized in juices, jellies, candies, teas, and alcoholic drinks. The fruits and flowers of the plant are used as pure meals colorants. Cactus gum is used to stiffen material. Important oils from the flowers are used to make perfumes, and the seeds are a supply of oil. Prickly pear has additionally been used as a supply of animal feed and dye.1, 4

There are quite a few medicinal makes use of of the plant. American Indians used prickly pear juice to deal with burns. Typically a cone of plant materials could be burned on the pores and skin to deal with irritation or an infection, a course of generally known as moxabustion in Chinese language medication. The Lakota tribe used prickly pear in a tea to help moms throughout childbirth.1

Prickly pear has an extended historical past of conventional Mexican people medication use, notably as a remedy for diabetes. Prickly pear pads have been used as a poultice for rheumatism. The fruit has been used for treating diarrhea, bronchial asthma, and gonorrhea. The fleshy stems or cladodes have been used to deal with excessive ldl cholesterol, blood stress, gastric acidity, ulcers, fatigue, dyspnea, glaucoma, liver circumstances, and wounds.1, Eight In South Korea the plant has been used to deal with belly ache, bronchial bronchial asthma, burns, diabetes, and indigestion.9 In Sicily, a flower decoction of prickly pear has been used as a diuretic; the cladodes had been valued for his or her anti-inflammatory exercise in treating edema, arthrosis, and whooping cough, and for stopping wound an infection.1

Prickly pear has additionally been planted on steep slopes to manage erosion.3

Chemistry

The medicinal parts of the plant are discovered within the flowers, leaves or pads, and fruit.

Isorhamnetin-glucoside, kaempferol, luteolin, penduletin, piscidic acids, quercetrin, rutin, and β-sitosterol have been discovered within the flowers of prickly pear.10 The leaves or pads are wealthy in mucilage and consist primarily of polysaccharides that include galactose, arabinose, xylose, and rhamnose.11

Prickly pear fruit is excessive in dietary worth.12 Ethanol-soluble carbohydrates are essentially the most ample parts of prickly pear fruit pulp and pores and skin, making up 50% of the pulp and 30% of the pores and skin. The betalain compounds are liable for the varied colours of the fruit.13 The pores and skin comprises calcium, iron, potassium, magnesium, manganese, sodium, and selenium.12, 14 The edible pulp comprises biothiols, taurine, flavonols, tocopherols, and carotenoids.15, 16 Nevertheless, industrial processing of juice parts ends in some lack of nutritional vitamins A, E, and C.8, 15 The seeds are wealthy in phosphorus and zinc. The oils from the seeds and peel are an excellent supply of polyunsaturated fatty acids.17, 18, 19

A number of older chemical analyses of enzymes from Opuntia species can be found.20, 21, 22, 23 One research paperwork the unstable constituents24 of prickly pear, whereas one other identifies the constituents of O. fragilis.25 Different research talk about the chemistry of prickly pear, together with isolation of albumin26 amino acid composition within the fruits27 and fatty acids of the seeds.28

Makes use of and Pharmacology

Diabetes

A mechanism of motion stays to be found in diabetes; nonetheless, polysaccharides could also be liable for the plant’s hypoglycemic exercise.29

Animal information

An extract of O. fulginosa prickly pear maintained regular blood glucose and glycated hemoglobin ranges in streptozotocin-induced diabetic rats after insulin was withdrawn.30 Comparable outcomes had been obtained with O. megacantha in lowering blood glucose in regular and streptozocin-induced diabetic rats. Nevertheless, O. megacantha was nephrotoxic as proven by elevated plasma urea and creatinine concentrations and diminished plasma sodium concentrations.31, 32

Scientific information

The hypoglycemic results of Opuntia species are documented in quite a few research.33, 34, 35, 36, 37, 38, 39 One open-label research of 14 sufferers discovered that O. streptacantha decreased glucose and insulin ranges in sufferers with noninsulin-dependent diabetes mellitus; nonetheless, the plant had no impact on glucose or insulin ranges in wholesome volunteers.36 One other open-label research involving 32 sufferers with kind 2 diabetes handled with O. streptacantha additionally resulted in decreased glucose and insulin ranges.40

Hyperlipidemia

Animal information

Two animal research examined the impact of prickly pear seed oil on serum and lipid parameters in rats.41, 42 A rise in high-density lipoprotein ldl cholesterol and a discount in serum ldl cholesterol was noticed in rats handled with seed oil. Uncooked O. ficus-indica had useful results on hypercholesterolemia in rats.43 A pectin isolate from Opuntia decreased low-density lipoprotein (LDL) metabolism in guinea pigs.44, 45, 46

Scientific information

In a single small research of 29 sufferers, prickly pear considerably diminished levels of cholesterol.35 Prickly pear might have antiplatelet exercise, which can be helpful in sufferers with prothrombotic circumstances reminiscent of diabetes and hyperlipidemia.47 Eight wholesome volunteers and eight sufferers with familial heterozygous hypercholesterolemia had been handled with prickly pear 250 mg for two months. Important (P > 0.01) decreases in whole and LDL-cholesterol and diminished platelet proteins had been discovered.

Opuntia capsules in a human trial had marginally useful results on ldl cholesterol and glucose ranges.48

Irritation

The mechanism of motion is related to the anti-inflammatory precept β-sitosterol.49

Animal information

Anti-inflammatory actions had been demonstrated in Opuntia dillenii in an induced rat paw edema mannequin.50 β-sitosterol from the recent stems of prickly pear had potent anti-inflammatory exercise in an adjuvant-induced power irritation mannequin in mice.49

Scientific information

Prickly pear might inhibit the manufacturing of inflammatory mediators related to the signs of alcohol hangover.51 In a double-blind, placebo-controlled, crossover trial, 55 wholesome volunteers acquired placebo or 1,600 items of prickly pear 5 hours earlier than consuming alcohol. Sufferers consumed 1.75 g alcohol/kg of physique weight over Four hours. C-reactive protein and signs reminiscent of nausea, dry mouth, and anorexia had been diminished in sufferers handled with prickly pear.

Ulcers

A cytoprotective mechanism is related to an interplay between the mucilage monosaccharides from prickly pear and membrane phospholipids.52, 53

Animal information

Histological proof helps the efficacy of prickly pear cladodes in opposition to the formation of ethanol-induced ulcers.54

Scientific information

No medical trials could possibly be discovered.

Different makes use of

Antioxidant

Opuntia species have antioxidant exercise which may be related to their phenolic content material.55 Quick-term supplementation with 250 g of recent fruit pulp in a comparative research56 and a research of sufferers with familial remoted hypercholesterolemia57 diminished oxidative harm to lipids and improved oxidative stress standing of handled sufferers.

Diuretic

Prickly pear cladode, fruit, and flower infusions elevated diuresis in a rat mannequin.58

Neuroprotective results

Animal fashions in rats demonstrated that the flavonoids remoted from O. ficus-indica var. saboten species had neuroprotective exercise in opposition to oxidative harm induced in cortical cell cultures and neuronal harm induced by international ischemia.9, 16, 59

Diet

Prickly pear fruit liquid has been studied as a pure sweetener.60Opuntia has been studied as a supply of dietary fiber.61

Viral exercise

One research experiences O. streptacantha antiviral motion in animals and people.62

Weight reduction

A meta-analysis of 5 blind randomized managed trials evaluated the proof for effectiveness of cactus pear (Opuntia ficus-indica) on physique weight and cardiovascular danger components. Evaluation of knowledge from research recognized by April 2014 revealed a nonsignificant distinction in physique weight and waist circumference between cactus pear and controls with statistically vital reductions in physique mass index (BMI), p.c physique fats, blood stress, and whole ldl cholesterol. Nevertheless, heterogeneity was excessive and danger of bias was extremely variable. Impact sizes for BMI and p.c physique fats reductions had been small and never clinically vital. Day by day dosages ranged from 400 mg to 15 g for durations of 6 weeks to 2 years.72

Wound therapeutic

Histological proof paperwork that topical utility of polysaccharide extracts from prickly pear cladodes enhanced cutaneous restore and therapeutic of huge, full-thickness wounds in a rat mannequin.63, 64 The polysaccharides from prickly pear cladodes have been studied for his or her chondroprotective results in treating joint ailments.65

Dosing

Prickly pear is commercially obtainable in quite a few doseforms, together with capsules, tablets, powders, and juices, and as meals. Comply with producers’ recommended pointers if utilizing industrial merchandise. Typical dosage regimens are two 250 mg capsules by mouth Three instances a day or each Eight hours.

Being pregnant / Lactation

Keep away from use throughout being pregnant and lactation due to the dearth of medical research.

Interactions

Prickly pear might theoretically exacerbate hypoglycemia in sufferers being handled with hypoglycemic brokers (eg, metformin, glyburide, rosiglitazone, acarbose).66 Prickly pear can also exacerbate diuresis in sufferers being handled with diuretic brokers (eg, furosemide, hydrochlorothiazide). Nevertheless, these interactions should not nicely documented.

Adversarial Reactions

Dermatitis from prickly pear is the most typical antagonistic response. A case report of cactus dermatitis in a 2-year-old baby was described after contact with O. microdasys.67 Two different sufferers had been additionally affected by this species, each experiencing dermatitis and one growing extreme keratoconjunctivitis in the precise eye.68 A case of cactus granuloma in a 24-year-old man is described from contact with O. bieglovii thorns.69 Granuloma formation has additionally been seen from O. acanthocarpa spines embedded within the dermis, with onset occurring inside a number of days and lasting a number of months. Therapy with topical corticosteroids has been beneficial.70, 71

Toxicology

Sufferers hypersensitive to any parts of prickly pear ought to keep away from use. O. streptacantha is unhazardous in mice, horses, and people in oral and intravenous preparations.62O. megacantha is nephrotoxic in rats.31, 32

Index Phrases

  • Opuntia acanthocarpa
  • Opuntia bieglovii
  • Opuntia dillenii
  • Opuntia fulginosa
  • Opuntia megacantha
  • Opuntia microdasys

References

1. DeFelice MS. Prickly pear cactus, Opuntia spp. A spine-tingling story. Weed Technol. 2004;18(3):869-877.2. Houérou HN. The function of cacti (Opuntia spp.) in erosion management, land reclamation, rehabilitation and agricultural improvement within the Mediterranean Basin. J Arid Environ. 1996;33(2):135-159.3. Synman HA. A greenhouse research on root dynamics of cactus pears, Opuntia ficus-indica and O. robusta. J Arid Environ. 2006;65(4):529-542.4. Saleem M, Kim HJ, Han CK, Jin C, Lee YS. Secondary metabolites from Opuntia ficus-indica var. saboten. Phytochemistry. 2006;67(13):1390-1394.167623825. van Sittert L. Our irrepressible fellow-colonist: the organic invasion of prickly pear (Opuntia ficus-indica) within the Jap Cape c.1890-c.1910. J Hist Geogr. 2002;28(3):397-419.6. Hocking GM. A Dictionary of Pure Merchandise. Medford, NJ: Plexis Publishing, Inc; 1997:546-547.7. Chevallier A. The Encyclopedia of Medicinal Vegetation. New York, NY: DK Publishing; 1996:240.8. Gurrieri S, Miceli L, Lanza CM, Tomaselli F, Bonomo RP, Rizzarelli E. Chemical characterization of Sicilian prickly pear (Opuntia ficus indica) and views for the storage of its juice. J Agric Meals Chem. 2000;48(11):5424-5431.110874969. Kim JH, Park SM, Ha HJ, et al. Opuntia ficus-indica attenuates neuronal harm in in vitro and in vivo fashions of cerebral ischemia. J Ethnopharmacol. 2006;104(1-2):257-262.10. D’Amelio FS. Botanicals: A Phytocosmetic Desk Reference. Boca Raton, FL: CRC Press; 1999:71.11. Matsuhiro B, Lillo LE, Sáenz C, Urzúa CC, Zárate O. Chemical characterization of the mucilage from fruits of Opuntia ficus indica. Carbohydr Polym. 2006;63(2):263-267.12. el Kossori RL, Villaume C, el Boustani E, Sauvaire Y, Méjean L. Composition of pulp, pores and skin and seeds of prickly pears fruit (Opuntia ficus indica sp.). Plant Meals Human Nutr. 1998;52(3):263-270.995008713. Butera D, Tesoriere L, Di Gaudio F, et al. Antioxidant actions of Sicilian prickly pear (Opuntia ficus indica) fruit extracts and lowering properties of its betalains: betanin and indicaxanthin. J Agric Meals Chem. 2002;50(23):6895-6901.1240579414. Galati EM, Mondello MR, Giuffrida D, et al. Chemical characterization and organic results of Sicilian Opuntia ficus indica (L.) Mill. Fruit juice: antioxidant and antiulcerogenic exercise. Agric Meals Chem. 2003;51(17):4903-4908.1290394315. Tesoriere L, Fazzari M, Allegra M, Livrea MA. Biothiols, taurine, and lipid-soluble antioxidants within the edible pulp of Sicilian cactus pear (Opuntia ficus-indica) fruits and modifications of bioactive juice parts upon industrial processing. J Agric Meals Chem. 2005;53(20):7851-7855.1619064116. Dok-Go H, Lee KH, Kim HJ, et al. Neuroprotective results of antioxidative flavonoids, quercetin, (+)-dihydroquercetin and quercetin 3-methyl ether, remoted from Opuntia ficus-indica var. saboten. Mind Res. 2003;965(1-2):130-136.1259112917. Ennouri M, Evelyne B, Laurence M, Hamadi A. Fatty acid composition and rheological behaviour of prickly pear seed oils. Meals Chemistry. 2005;93(3):431-437.18. Ramadan MF, Mörsel JT. Oil cactus pear (Opuntia ficus-indica L.). Meals Chem. 2003;82(3):339-345.19. Ramadan MF, Mörsel JT. Recovered lipids from prickly pear (Opuntia ficus-indica [L.] Mill) peel: an excellent supply of polyunsaturated fatty acids, pure antioxidant nutritional vitamins and sterols. Meals Chem. 2003;83(3):447-456.20. Mukerji SK, Ting IP. Malate dehydrogenase (decarboxylating) (NADP) isoenzymes of Opuntia stem tissue. Mitochondrial, chloroplast, and soluble kinds. Biochim Biophys Acta. 1968;167(2):239-249.438925321. Mukerji S, Ting IP. Malic dehydrogenase isoenzymes in inexperienced stem tissue of Opuntia isolation and characterization. Arch Biochem Biophys. 1969;131(2):336-351.430682222. Sisini A. On glucose-6-phosphate isomerase in Opuntia ficus indica [in Italian]. Boll Soc Ital Biol Sper. 1969;45(12):794-796.537517223. Bhatia D, Malik CP. Histochemical research in stomatal equipment of Phaseolus mungo Linn, Lathyrus sativus Linn and Opuntia elatior Mill. Folia Histochem Cytochem (Krakow). 1977;15(4):315-332.59877224. Flath RA, Takahashi JM. Risky constituents of prickly pear (Opuntia ficus indica Mill., de Castilla selection). J Agric Meals Chem. 1978;26(4):835-837.25. Abramovitch R, Coutts RT, Knaus EE. Identification of constituents of Opuntia fragilis. Planta Med. 1968;16(2):147-157.570389226. Uchoa A, Souza PA, Zarate RM, Gomes-Filho E, Campos FA. Isolation and characterization of a reserve protein from the seeds of Opuntia ficus-indica (Cactaceae). Braz J Med Biol Res. 1998;31(6):757-761.969881927. Stintzing F, Schieber A, Carle R. Amino acid composition and betaxanthin formation in fruits from Opuntia ficus-indica. Planta Med. 1999;65(7):632-635.1726028828. Barbagallo R, et al. Dedication of fatty acids in oil from seeds of Opuntia ficus-indica L. (Miller). Indian Aliment. 1999;38:815-817.29. Alarcon-Aguilar FJ, Valdes-Arzate A, Xolalpa-Molina S, et al. Hypoglycemic exercise of two polysaccharides remoted from Opuntia ficus-indica and O. streptacantha. Proc West Pharmacol Soc. 2003;46:139-142.1469991230. Trejo-González A, Gabriel-Ortiz G, Puebla-Pérez AM, et al. A purified extract from prickly pear cactus (Opuntia fuliginosa ) controls experimentally induced diabetes in rats. J Ethnopharmacol. 1996;55(1):27-33.912116431. Bwititi P, Musabayane CT, Nhachi CF. Results of Opuntia megacantha on blood glucose and kidney operate in streptozotocin diabetic rats. J Ethnopharmacol. 2000;69(3):247-252.1072220732. Bwititi PT, Machakaire T, Nhachi CB, Musabayane CT. Results of Opuntia megacantha leaves extract on renal electrolyte and fluid dealing with in streptozotocin (STZ)-diabetic rats. Ren Fail. 2001;23(2):149-158.1141794733. Roman-Ramos R, Flores-Sáenz JL, Partida-Hernández G, Lara-Lemus A, Alarcón-Aguilar F. Experimental research of the hypoglycemic impact of some antidiabetic crops. Arch Make investments Med (Mex). 1991;22(1):87-93.181998134. Ibanez-Camacho R, Roman-Ramos R. Hypoglycemic impact of Opuntia cactus. Arch Make investments Med (Mex). 1979;10(4):223-230.53986535. Frati-Munari A, Fernández-Harp JA, Bañales-Ham M, Ariza-Andraca CR. Decreased blood glucose and insulin by nopal (Opuntia sp.). Arch Make investments Med (Mex). 1983;14 (3):269-274.636768536. Frati A, Gordillo BE, Altamirano P, Ariza CR, Cortés-Franco R, Chavez-Negrete A. Acute hypoglycemic impact of Opuntia streptacantha Lemaire in NIDDM. Diabetes Care. 1990;13(4):455-456.231811037. Frati-Munari A, Licona-Quesada R, Araiza-Andraca CR, López-Ledesma R, Chávez-Negrete A. Exercise of Opuntia streptacantha in wholesome people with induced hyperglycemia [in Spanish]. Arch Make investments Med (Mex). 1990;21 (2):99-102.210371338. Frati A, Xilotl Díaz N, Altamirano P, Ariza R, López-Ledesma R. The impact of two sequential doses of Opuntia streptacantha upon glycemia. Arch Make investments Med (Mex). 1991;22(3-4):333-336.184412139. Roman-Ramos R, Flores-Saenz JL, Alarcon-Aguilar FJ. Anti-hyperglycemic impact of some edible crops. J Ethnopharmacol. 1995;48(1):25-32.856924440. Yeh GY, Eisenberg DM, Kaptchuk TJ, Phillips RS. Systematic overview of herbs and dietary dietary supplements for glycemic management in diabetes. Diabetes Care. 2003;26(4):1277-1294.1266361041. Ennouri M, Fetoui H, Bourret E, Zeghal N, Attia H. Analysis of some organic parameters of Opuntia ficus indica. 2. Affect of seed supplemented eating regimen on rats. Bioresour Technol. 2006;97(12):1382-1386.1612960142. Ennouri M, Fetoui H, Hammami M, Bourret E, Attia H, Zeghal N. Results of eating regimen supplementation with cactus pear seeds and oil on serum and liver lipid parameters in rats. Meals Chem. 2007;101(1):248-253.43. Cardenas Medellin ML, Serna Saldivar SO, Velazco de la Garza J. Impact of uncooked and cooked nopal (Opuntia ficus indica) ingestion on progress and profile of whole ldl cholesterol, lipoproteins, and blood glucose in rats [in Spanish]. Arch Latinoam Nutr. 1998;48(4):316-323.1034769644. Fernandez ML, Trejo A, McNamara DJ. Pectin remoted from prickly pear (Opuntia sp.) modifies low density lipoprotein metabolism in cholesterol-fed guinea pigs. J Nutr. 1990;120(11):1283-1290.223101845. Fernandez M, Lin EC, Trejo A, McNamara DJ. Prickly pear (Opuntia sp.) pectin alters hepatic ldl cholesterol metabolism with out affecting ldl cholesterol absorption in guinea pigs fed a hypercholesterolemic eating regimen. J Nutr. 1994;124(6):817-824.820753946. Fernandez ML, Lin EC, Trejo A, McNamara DJ. Prickly pear (Opuntia sp.) pectin reverses low density lipoprotein receptor suppression induced by a hypercholesterolemic eating regimen in guinea pigs. J Nutr. 1992;122(12):2330-2340.133352047. Wolfram R, Budinsky A, Efthimiou Y, Stomatopoulos J, Oguogho A, Sinzinger H. Day by day prickly pear consumption improves platelet operate. Prostaglandin Leukot Essent Fatty Acids. 2003;69(1):61-66.48. Frati Munari AC, Vera Lastra O, Ariza Andraca CR. Analysis of nopal capsules in diabetes mellitus [in Spanish]. Gac Med Mex. 1992;128(4):431-436.130799449. Park EH, Kahng JH, Lee SH, Shin KH. An anti-inflammatory precept from cactus. Fitoterapia. 2001;72(3):288-290.1129530850. Loro J, del Rio I, Pérez-Santana L. Preliminary research of analgesic and anti inflammatory properties of Opuntia dillenii aqueous extract. J Ethnopharmacol. 1999;67(2):213-218.1061938651. Wiese J, McPherson S, Odden MC, Shlipak MG. Impact of Opuntia ficus indica on signs of the alcohol hangover. Arch Intern Med. 2004;164(12):1334-1340.1522616852. Vazquez-Ramirez R, Olguin-Martinez M, Kubli-Garfias C, Hernandez-Munoz R. Reversing gastric mucosal alterations throughout ethanol-induced power gastritis in rats by oral administration of Opuntia ficus-indica mucilage. World J Gastroenterol. 2006;12(27):4318-4324.1686577253. Galati EM, Monforte MT, Miceli N, et al. Opuntia ficus indica (L.) Mill. mucilages present cytoprotective impact on gastric mucosa in rat. Phytother Res. 2007;21(4):344-346.1722182854. Galati EM, Monforte MT, Tripodo MM, d’Aquino A, Mondello MR. Antiulcer exercise of Opuntia ficus indica (L.) Mill. (Cactaceae): ultrastructural research. J Ethnopharmacol. 2001;76(1):1-9.55. Lee JC, Kim HR, Kim J, Jang YS. Antioxidant property of an ethanol extract of the stem of Opuntia ficus-indica var. Saboten. J Agric Meals Chem. 2002;50(22):6490-6496.1238113856. Tesoriere L, Butera D, Pintaudi AM, Allegra M, Livrea MA. Supplementation with cactus pear (Opuntia ficus-indica) fruit decreases oxidative stress in wholesome people: a comparative research with vitamin C. Am J Clin Nutr. 2004;80(2):391-395.1527716057. Budinsky A, Wolfram R, Oguogho A, Efthimiou Y, Stamatopoulos Y, Sinzinger H. Common ingestion of opuntia robusta lowers oxidation harm. Prostaglandins Leukot Essent Fatty Acids. 2001;65(1):45-50.58. Galati EM, Tripodo MM, Trovato A, Miceli N, Monforte MT. Organic impact of Opuntia ficus indica (L.) Mill. (Cactaceae) waste matter: Be aware I: diuretic exercise. J Ethnopharmacol. 2002;79(1):17-21.1174429059. Kwak KP. Neuroprotective results of the flavonoids remoted from Opuntia ficus-indica var. saboten. Eur Neuropsychopharmacol. 2005;15(suppl 3):S567.60. Saenz C, Estévez AM, Sepúlveda E, Mecklenburg P. Cactus pear fruit: A brand new supply for a pure sweetner. Plant Meals Hum Nutr. 1998;52(2):141-149.983981361. Rosado JL, Diaz M. Physico-chemical properties associated to gastrointestinal operate of 6 sources of dietary fiber [in Spanish]. Rev Make investments Clin. 1995;47(4):283-299.852513062. Ahmad A, Davies J, Randall S, Skinner GR. Antiviral properties of extract of Opuntia streptacantha. Antiviral Res. 1996;30(2-3):75-85.63. Park EH, Chun MJ. Wound therapeutic exercise of Opuntia ficus-indica. Fitoterapia. 2001;72(2):165-167.1122322664. Trombetta D, Puglia C, Perri D, et al. Impact of polysaccharides from Opuntia ficus-indica (L.) cladodes on the therapeutic of dermal wounds within the rat. Phytomedicine. 2006;13(5):352-358.1663574365. Panico AM, Cardile V, Garufi F, Puglia C, Bonina F, Ronsisvalle S. Impact of hyaluronic acid and polysaccharides from Opuntia ficus indica (L.) cladodes on the metabolism of human chondrocyte cultures. J Ethnopharmacol. 2007;111(2):315-321.1719677766. Bush TM, Rayburn KS, Holloway SW, et al. Adversarial interactions between natural and dietary substances and prescription drugs: a medical survey. Altern Ther Well being Med. 2007;13(2):30-35.1740567667. Vakilzadeh F, Bröcker EB. Cactus dermatitis [in German]. Z Hautkr. 1981;56(19):1299-1301.731476068. Whiting DA, Bristow JH. Dermatitis and keratoconjunctivitis attributable to a prickly pear (Opuntia microdasys). S Afr Med J. 1975;49(35):1445-1448.116636269. Suzuki H, Baba S. Cactus granuloma of the pores and skin. J Dermatol. 1993;20(7):424-427.840892470. Spoerke DG, Spoerke SE. Granuloma formation induced by spines of the cactus, Opuntia acanthocarpa. Vet Hum Toxicol. 1991;33(4):342-344.189712971. Yoon HJ, Gained CH, Moon SE. Allergic contact dermatitis resulting from Opuntia ficus-indica var. saboten. Contact Derm. 2004;(51):311-322.1560665872. Onakpoya IJ, O’Sullivan J, Heneghan CJ. The impact of cactus pear (Opuntia ficus-indica) on physique weight and cardiovascular danger components: a scientific overview and meta-analysis of randomized medical trials. Diet. 2015;31(5):640-646.25837206

Disclaimer

This info pertains to an natural, vitamin, mineral or different dietary complement. This product has not been reviewed by the FDA to find out whether or not it’s secure or efficient and isn’t topic to the standard requirements and security info assortment requirements which are relevant to most prescribed drugs. This info shouldn’t be used to determine whether or not or to not take this product. This info doesn’t endorse this product as secure, efficient, or authorized for treating any affected person or well being situation. That is solely a quick abstract of normal details about this product. It does NOT embrace all details about the doable makes use of, instructions, warnings, precautions, interactions, antagonistic results, or dangers that will apply to this product. This info is just not particular medical recommendation and doesn’t exchange info you obtain out of your well being care supplier. It’s best to speak along with your well being care supplier for full details about the dangers and advantages of utilizing this product.

This product might adversely work together with sure well being and medical circumstances, different prescription and over-the-counter medicine, meals, or different dietary dietary supplements. This product could also be unsafe when used earlier than surgical procedure or different medical procedures. It is very important absolutely inform your physician concerning the natural, nutritional vitamins, mineral or every other dietary supplements you take earlier than any sort of surgical procedure or medical process. Except sure merchandise which are usually acknowledged as secure in regular portions, together with use of folic acid and prenatal nutritional vitamins throughout being pregnant, this product has not been sufficiently studied to find out whether or not it’s secure to make use of throughout being pregnant or nursing or by individuals youthful than 2 years of age.

Additional info

All the time seek the advice of your healthcare supplier to make sure the data displayed on this web page applies to your private circumstances.

admin

Leave a Reply

Your email address will not be published. Required fields are marked *

Back to top